Inverted dT can be introduced at the 3’-end of an oligonucleotide to create a 3’-3’ linkage that stops DNA polymerase from further extending the DNA sequence. Additionally, inverted dT protects the oligonucleotide from 3’ exonuclease cleavage.
Metabion offers inverted-dT in its DNA portfolio. Click here
|Extinction coefficient (260 nm)||8.4 mM-1cm-1|