DNA Oligos - plates

The “classic” definition of High Throughput Oligos goes back to the needs for large numbers of mainly unmodified, moderately long standard oligos delivered in microtiter plate formats to suit the requirements of increasingly popular Genomic screening/microarray programs.

From the beginning, metabion recognized the risk of compromised quality coming along with mass production of oligonucleotides. Hence, we were determined to prove, that our slogan “quantity meets quality” comes alive by developing our own high throughput technology platform to produce HTOs (High Througput Oligos).

“Heart” of this platform is our inhouse developed 96-Parallel Synthesizer, called BH96 (“Blue Hedgehog” 96), which gives us the chance to produce high throughput-high quality oligos, a unique feature we are very proud to build on. The uniqueness of our BH96 is convincingly reflected by the fact that metabion could protect the instrument by patent! As quality was, is, and will always be metabion´s first priority, the “kidney” of our HTO line is Sequenom´s MassArray System, which enables us to check each and every oligo produced by Maldi-ToF. With the help of this specially adapted system, we can “filter” our synthesis products very quickly for potential quality nonconformities referring to our stringently applied quality criteria. Non-conform oligos are immediately re-synthesized so that only completely checked and approved plates are released.

Our outstanding performance in terms of High Throughput Oligos synthesis is based on

  • Quantity delivered: we guarantee delivery amounts based on final yields in nmol, rather than on abstract OD260 values
  • Quality guarantee: metabion has been the first company in Europe to introduce 100% quality check by Maldi-ToF, and yet being able to offer oligos in plates at best value prices.

Our commitment to quality is further emphasized by our production procedures having been ISO certified according to DIN EN 9001 and 13485 since 2001 and 2010, respectively.

Our standard custom DNA Oligos - MTP plate format Portfolio

 

Delivery in 96well microtiter plates. 

  • 1.2 ml round well/U-bottomed
  • 1.0 ml “Matrix” microplates w/o barcode
  • 1.0 ml “Matrix” microplates 2D barcoded 

3 yield ranges* based on length independent delivered quantities* from 11-80 nmol.

  • ≥ 10 < 25 nmol
  • ≥ 25 < 50 nmol
  • ≥ 50 < 100 nmol

 

DNA Oligos - MTP plate format - Modifications
  Position
Modifications
5'-end 3'-end
6-Fam  ✓  
Fluo  ✓  
Biotin  ✓  ✓
Phosphate  ✓  
C6 Amino  ✓  
C7 Amino  
C12 Amino  ✓  
Inosine   ✓  

We can also ship your oligos wet at the following concentrations:

  Yield Range (nmol)
Concentration (µM) ≥10<25 nmol ≥25<50 nmol ≥50<100 nmol
50 µM  ✓  ✓  
100 µM  ✓  ✓  ✓
200 µM  ✓  ✓  ✓
300 µM  ✓  ✓  ✓
400 µM  ✓  ✓  ✓
500 µM  ✓  ✓  ✓
DNA Oligo price list download PDF

For HPLC purified oligos in MTP format, please inquire.

 

 

Order Forms

DNA Oligos - MTP plate format  download xls
Also available in our web order system (WOP)

Credit Card Payment Form

Credit Card Payment Form download PDF

Price List

DNA Portfolio price list
download PDF