Extended primer portfolio:
- 4 standard ZNA building block modifications: ZNA-2, ZNA-3, ZNA-4, and ZNA-5!
ZNA-2 for oligos ≥ 8mers new!
ZNA-3 for oligos ≥ 12mers new!
ZNA-4 for oligos ≥ 16mers
ZNA-5 for oligos ≥ 20mers
- Standard length range from 8 to 40mers
- Documented Mass-Check QC included
- 5 standard scales (yield ranges in nmoles)
- “Add-on“ modification prices for ZNA building blocks (see table 1 below)
- “Add-on“ modification prices for base analoga (pdC, pdU; see table 2 below)
Table 1: ZNA building block pricing
| Primer 5' Modification |
Scale
Yield range (><)* in nmol |
ZNA-2
Price in € |
ZNA-3
Price in € |
ZNA-4
Price in € |
ZNA-5
Price in € |
| >/= 5 <10 |
40.00 |
45.00 |
50.00 |
65.00 |
| >/=10 <20 |
60.00 |
65.00 |
70.00 |
85.00 |
| >/=20 <30 |
80.00 |
85.00 |
90.00 |
105.00 |
| >/=30 <50 |
100.00 |
105.00 |
110.00 |
125.00 |
| >/=50 <70 |
115.00 |
120.00 |
125.00 |
155.00 |
| >/=70 |
please inquire |
| *based on oligonucleotides of 8-40 bases in length |
Table 2: Base analoga pricing- primers
| Base analoga pricing- primers |
| |
Pricing (€) per base analoga substitution |
Scale
Yield range (><)* in nmol |
pdC |
pdU |
| >/= 5 <10 |
25.00 |
20.00 |
| >/=10 <20 |
40.00 |
30.00 |
| >/=20 <30 |
55.00 |
45.00 |
| >/=30 <50 |
75.00 |
65.00 |
| >/=50 <70 |
90.00 |
80.00 |
| >/=70 |
please inquire |
| *based on oligonucleotides of 8-40 bases in length |
Extended probes portfolio:
- 3 standard ZNA-Quencher (Q*ZNA-X) building block modifications for 3´labeling. Respective choice of 3´building blocks will be made automatically by metabion according to the following scheme:
3´ Q*ZNA-2 for probes ≥ 10mers
3´ Q*ZNA-3 for probes ≥ 14mers
3´ Q*ZNA-4 for probes ≥ 18mers
- For 5´ ZNA-Reporter labeling, please inquire! Applying Click-chemistry, we shall be able to accommodate a lot of requirements, which could not be realized before. Feel free to discuss your ideas and needs with us.
- Various Reporter/Quencher combinations at 3 complexity/pricing levels (see table 3 below).
- Standard length range from 10 to 40mers.
- 5 standard scales (yield ranges in nmoles).
- Fixed prices per probe according to scale and pricing level (see table 4 below).
- “Add-on“ modification prices for base analoga (pdC, pdU; see table 5 below).
- Documented Mass-Check QC included.
Table 3: Reporter/Quencher combinations
| 3' Quencher |
| |
BHQ-1 |
BHQ-2 |
Eclipse |
Dabcyl |
|
|
|
| Abs range (nm) |
480-580 |
550-650 |
390-625 |
380-550 |
|
|
|
| Abs max (nm) |
535 |
579 |
522 |
453 |
|
|
|
| 5' Reporter |
Pricing Level |
Abs (nm)* |
Em (nm)* |
Color |
| Fluo |
1 |
- |
1 |
1 |
495 |
520 |
|
| 6-FAM |
1 |
- |
1 |
1 |
495 |
520 |
|
| Rhodamine Green |
3 |
- |
3 |
3 |
503 |
528 |
|
| TET |
3 |
- |
3 |
3 |
521 |
536 |
|
| JOE |
2 |
- |
2 |
2 |
522 |
548 |
|
| Yakima Yellow |
2 |
- |
2 |
2 |
530 |
549 |
|
| Hex |
2 |
2 |
2 |
2 |
535 |
556 |
|
| Cy3 |
- |
2 |
- |
- |
546 |
563 |
|
| ROX |
3 |
3 |
3 |
- |
576 |
601 |
|
| Texas Red |
- |
3 |
3 |
- |
586 |
610 |
|
| LC®Red 610 |
- |
3 |
3 |
- |
590 |
610 |
|
| LC®Red 640 |
- |
3 |
- |
- |
625 |
640 |
|
| Cy5 |
- |
2 |
- |
- |
646 |
662 |
|
| Cy5.5 |
- |
2 |
- |
- |
683 |
705 |
|
| IRD 700 |
- |
2 |
- |
- |
685 |
705 |
|
| *Please note that absorption and emission wavelengths are influenced by the solvent (pH, salt conditions, etc.), oligo sequence and other factors. |
Table 4: “ZNA probes” pricing
ZNA probes pricing
Pricing level |
Scale
Yield range (><)* in nmol |
1
Price in € |
2
Price in € |
3
Price in € |
# of tests @ 2 pmol probe/ rxn
(10 µl rxn vol) |
| >/= 5 <10 |
160.00 |
220.00 |
280.00 |
3.250,00 |
| >/=10 <20 |
185.00 |
255.00 |
325.00 |
7.500,00 |
| >/=20 <30 |
225.00 |
315.00 |
405.00 |
12.500,00 |
| >/=30 <50 |
330.00 |
430.00 |
560.00 |
20.000,00 |
| >/=50 <70 |
520.00 |
580.00 |
750.00 |
30.000,00 |
| >/=70 |
please inquire |
| *based on oligonucleotides of 10-40 bases in length |
Table 5: Base analoga pricing - probes
| Base analoga pricing- probes |
| |
Pricing (€) per base analoga substitution |
Scale
Yield range (><)* in nmol |
pdC |
pdU |
| >/= 5 <10 |
25.00 |
20.00 |
| >/=10 <20 |
40.00 |
30.00 |
| >/=20 <30 |
55.00 |
45.00 |
| >/=30 <50 |
75.00 |
65.00 |
| >/=50 <70 |
90.00 |
80.00 |
| >/=70 |
please inquire |
| *based on oligonucleotides of 10-40 bases in length |
