We are pleased to present MEX, a highly stable and sensitive alternative to HEX, to our extensive portfolio of modifications.
MEX (Dichloro-diphenyl-fluorescein) is the metabion alternative to HEX. Although widely used, this old dye suffers from chemical instability, which is problematic during oligonucleotide synthesis as well as in down-stream assays due to the presence of byproducts.
MEX is virtually identical in terms of chemical structure, and therefore has practically identical fluorescent properties. However, MEX is much more stable, both during synthesis as well as in experiments, making it the best choice for your assays.
Why switch to MEX?
- MEX is practically identical to HEX, making it easy to integrate MEX in all your existing workflows
- MEX shines with a high molecular extinction coefficient, quantum yield and resistance to photobleaching
- MEX is highly stable during oligosynthesis, leading to fewer byproducts and high-quality probes
- MEX offers maximum sensitivity and stability in quantitative and multiplex assays across all PCR cycles
- MEX is entirely licence-free
MEX is available for many probes in our qPCR probe portfolio, such as Dual-Labelled Probes, High Performance Double Quenched Probes, as well as MGB and LNA Probes.
MEX is compatible with MBQ-1, BHQ®-1 and Eclipse quenchers.
Any questions? Get in touch with our team of experts.
Download the product flyer for a quick technical overview.