What scales are offered for metabion custom RNA oligonucleotides in single tube format?
Desalted
4 yield ranges based on length-independent delivered quantities from 10-100 nmol for single-stranded oligos from 5-40 nucleotides.
- ≥ 10 < 25 nmol
- ≥ 25 < 50 nmol
- ≥ 50 < 100 nmol
- ≥ 100 nmol
HPLC-purified
5 yield ranges based on length independent delivered quantities* from 5-400 nmol for oligos from 2-80 nucleotides:
- ≥ 5 < 25 nmol
- ≥ 25 < 50 nmol
- ≥ 50 < 100 nmol
- ≥ 100 < 200 nmol
- ≥ 200 < 400 nmol
* Please note that the term “yield range” refers to the final amount of product you will actually receive. Instead, OD260 values are a measure of total nucleotide optical density. Hence, neither purity nor amount of ordered substance are transparently reflected. For simplification and exemplification reasons look at the following:
1 OD of the 20mer 5´cau cgu auu cga ugc uac gu 3´ translates into approximately 5 nmol;
1 OD of the 40mer 5´cau cgu auu cga ugc uac guc auc gua uuc gau gcu acg u 3´ translates into approximately 2.5 nmol.
Therefore, a 1 OD guaranteed amount of delivered product can vary significantly, while metabion´s commitment to delivered yields in nmol for RNAs ranging from 2 to 80 nucleotides does not allow for ambiguity in terms of what you expect and pay for, not even for modified oligos!