Therapeutic Oligonucleotides
- From R&D to GMP grade manufacturing, from Research to Clinics
- Lead Discovery
- Lead Optimization
- Preclinical Development
- Clinical Trials
- Support and Services include
- Design of Experiment (DOE)
- Process Characterization
- Process Development
- Process Validation
- IND & NDA Filing support
- Scale-up & Process Transfer
- Portfolio covering most prevalent types of therapeutic oligonucleotides
- CpG oligonucleotides - excipients/adjuvants
- Antisense oligonucleotides (ASOs)
- siRNA
- Gapmers/RNA-DNA Chimera
- miRNA
- sgRNA for CRISPR/Cas technology
- Aptamers
- Oligonucleotide-peptide/lipid/sugar conjugates for tissue specific API delivery