Quality to trust

Your trusted partner for custom oligonucleotide synthesis

With three decades of experience, we deliver high-quality oligonucleotides to customers worldwide, supporting applications from research and diagnostics to therapeutic development.

With ISO 9001 and ISO 13485 certification and a team of experienced chemists, we specialise in customised oligonucleotide solutions, combining technical expertise with the flexibility to meet your specific requirements.

Custom solutions

An oligo boutique for complex requirements

With a team of experienced scientists, we specialize in oligonucleotides with complex and custom requirements. Our portfolio includes one of the most comprehensive ranges of oligonucleotide modifications available worldwide.

Can’t find the modification you need? Get in touch with our experts to discuss your requirements and explore the possibilities.

Polymerases and PCR Master Mixes

Reliable PCR all summer long!

When diagnostic accuracy matters, reliable performance is essential. Our PCR polymerases and ready-to-use PCR master mixes deliver efficient amplification and consistent results for demanding molecular diagnostic workflows.

With high-quality oligonucleotides and the reagents you need for PCR, we provide a complete solution from a single trusted source.

Your Oligo is our Expertise

Custom DNA Oligonucleotides

Modified and unmodified oligos for many applications, ranging from cloning, sequencing, hybridization (FISH) to molecular assays

qPCR Probes

Discover one of the most complete portfolios of fluorophores and quenchers for your qPCR, RT-PCR and digital PCR experiments

Custom RNA Oligonucleotides

Explore our RNA portfolio for RNA interference, CRISPR-Cas9 gene editing, and a wide range of molecular assays

m-blocks

Highly customizable gene fragments and DNA libraries for antibody and enzyme engineering projects

NGS

Reliable NGS solutions for high-confidence sequencing with minimized cross-contamination risk through our proprietary production process

Life Science Products

For all your PCR needs in addition to oligonucleotides, including enzymes, kits, and reagents

Mid- and Large Scale Services

Diagnostic and IVD Oligonucleotides

As an experienced oligoprovider for the diagnostics and IVD industry, we deliver high-quality oligonucleotides tailored to the stringent requirements of assay development and commercial manufacturing. From medium-scale batches to large-scale production programs, we provide reliable supply solutions that support every stage of your product lifecycle. Our commitment to quality is reflected in robust processes, comprehensive quality controls, and internationally recognized ISO-certified manufacturing standards, ensuring consistency, traceability, and performance you can trust. 

Therapeutic Oligonucleotides

Therapeutic oligonucleotide development requires precision, flexibility, and deep technical expertise. We support discovery and preclinical programs with custom oligonucleotide solutions tailored to diverse therapeutic modalities and research needs. With medium- and large-scale production capabilities, rigorous quality controls, and ISO-certified processes, we help accelerate innovation while ensuring consistent quality and reliable performance.

News from metabion

Meet MEX: the metabion alternative to HEX

We are pleased to present MEX, a highly stable and sensitive alternative to HEX, to our extensive portfolio of modifications. 

Introducing Our Updated DNA Portfolio

We are excited to introduce our updated DNA portfolio, designed to support research, clinical laboratories and diagnostic providers with an expanded range of modifications and increased flexibility.

New: Quotation Tool in the WebOrderPortal

Create quotes yourself in our Web Order Portal so you can order faster and more efficiently. 

We are here to support you!

Web Order Portal

Design and order your custom oligos and probes directly in our webshop.

Talk to an Expert

Do you have a complex request? Get in touch with our team of highly qualified scientists.

Knowledge Hub

Find more in-depth information about our products and applications.

About metabion

metabion is a biotechnology company with headquarters in Munich/Planegg. Founded at the end of 1997, the company is one of the world’s leading manufacturers of high-quality custom oligonucleotides. 

With its vast experience and innovative technologies, processes and methods, the company is a “boutique” and most complete custom oligo provider globally. We deliver to more than 80 countries around the world. ‘Best-in-class’ is our claim, supplying high-quality products and services adhering to the motto “quantity meets quality”. 

It all follows our vision to be the service provider of premium custom oligonucleotides. “Driving and supporting scientific progress and translating it into diagnostic and therapeutic solutions is our mission.”