2-Aminopurine

2-Aminopurine (Figure 1) is an adenine and guanine analog, which can pair with either thymine or cytosine. It is fluorescent and it is usually applied in DNA conformational studies.

Figure 1. Structure of 2-Aminopurine (R = sequence).

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References

Persing DH., McGinty L., Adams CW., Fowler RG. Mutational specificity of the base analogue, 2-aminopurine, in Escherichia coli. Mutat Res. 1981 Aug;83(1):25-37.