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2’-Deoxyuridine (Figure 1) can be incorporated in DNA oligonucleotides as an analog of dT. This base can be removed by treatment with uracil-N-deglycosylase (UNG), which is normally used to digest amplified DNA and eliminates DNA-RNA cross-contaminations.

2’-Deoxyuridine modified oligos can be used to study adaptive and innate immunity in animals.

Figure 1. Structure of 2’-Deoxyuridine (R = sequence).

metabion offers 2’-Deoxyuridine in its DNA and RNA portfolio: