Tamra is a Carboxytetramethylrhodamine, a derivative of rhodamine. Tamra represents an excellent alternative to NED and it is commonly used as FRET acceptor for FAM fluorophore, in real-time or automated DNA sequencing applications.
5-Tamra-Azide (Figure 1) is an azide modifier that can be used in Click-Chemistry. This technique allows multiple alkynated sites within an oligonucleotide to be labelled by “clicking” a variety of azide-containing labels/tags. To learn more about click-chemistry, click here.
Figure 1. Structure of 5-Tamra-Azide.
metabion offers 5-Tamra-Azide as a modification in its click-chemistry portfolio: