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BHQ®-3 (Figure 1) stands for Black Hole Quencher 3 and it consists of a dark quencher, often used in dual-labelled probes. As dark quenchers, Black Hole Quenchers absorb energy without emitting fluorescence. They are in fact non-fluorescent chromophores.

Figure 1. Structure of 5'-BHQ®-3 (R = sequence).

metabion offers BHQ®-3 modification in its DNA portfolio:

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