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Amine modifiers are employed to incorporate a primary amine group (NH2) into an oligonucleotides (Figure 1).

This modification allows for subsequent post-synthesis conjugation of the oligonucleotide with a variety of different moieties, like fluorescent dyes, quenchers, haptens, etc.

Figure 1. Structure of C2-Amino-dT (R = sequence).

metabion offers C2-Amino-dT as an internal modification in its standard DNA portfolio:

For more information, please visit our Portfolio. To place an order, click here.