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DBCO

DBCO (Figure 1) is usually used in copper-free click reactions, where DBCO-modified oligos and azide modifiers are conjugated in organic solvents, such as DMSO, or aqueous buffers.


Figure 1. Structure of 5'-DBCO (R = sequence).



metabion offers DBCO as a 5'-, 3'- or internal modification in its DNA portfolio: